Wake BioHotel: Luxury Hotel in Medellín, Colombia

In Medellín, a hotel is rethinking sleep, nutrition, and recovery from the ground up. Wake BioHotel invites you to slow down in order to live longer. Here, wellness stops being a slogan and becomes an exact science.
Wake BioHotel

Images courtesy Wake BioHotel

Wake BioHotel — Colombia’s First Sanctuary for Longevity



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El Poblado, an urban sanctuary in the city of eternal spring

Tucked into El Poblado, one of Medellín’s most vibrant neighborhoods, Wake BioHotel enjoys a mild, year-round climate and a backdrop of lush green mountains that frame the city. Known as the “city of eternal spring,” Medellín pairs cultural energy with generous nature, from parks to specialty cafés and contemporary art galleries. The hotel sits just minutes from Parque El Poblado, on a quiet residential street far from the bustle of downtown. Guests arrive expecting an urban stay and quickly realize it is something else entirely: a parenthesis built for regeneration, in the heart of Colombia.

Colombia’s first longevity hotel

Backed by the Wake group, already known in Medellín for its branded residences, Wake BioHotel was built to answer a simple question: what if luxury hospitality finally served health itself? The property stands as the country’s first hotel to bring a longevity club, biohacking therapies, and real food together under one roof. The concept goes far beyond occasional wellness: it embraces longevity as a way of life, pairing the rigor of the latest medical science with some of the oldest holistic practices. Every space, every protocol, every plate is designed with one goal in mind, that the effects of the stay outlast the checkout itself.

A minimalist design built for well-being

Wake BioHotel’s interior architecture embraces a deliberately pared-back, almost monastic aesthetic, where every line serves a sense of calm. Raw, non-toxic materials, neutral palettes, and carefully controlled light come together in a biophilic design that blurs the line between indoors and nature. Nothing is left to chance: airflow, surface texture, and room acoustics all play their part in this pursuit of regeneration. The result is a hotel that never seeks to impress through excess, but to soothe through the precision of every detail, striking a rare balance between sophistication and restraint.

One hundred and nine rooms built for absolute sleep

Wake BioHotel counts one hundred and nine rooms across six categories, from the compact, functional Classic Standard to the spectacular BioRoom Junior Suite, a true sleep laboratory. In between, the Standard Twin and Junior Twin suit stays among friends, while the Junior Suite with Living Room and Junior Suite with Bathtub offer more space and a private tub to extend the sense of ease. Every room shares the same standard: total window blackout, reinforced soundproofing, and a king-size bed fitted with bio-optimized add-ons. The BioRoom Junior Suite goes further still, with a temperature-regulated mattress, an infrared PEMF mat, and Therabody smart goggles, turning every night into an active recovery session.

Silo, where nutritious becomes delicious

On the sixth floor, Silo restaurant embodies the hotel’s philosophy: real, traceable food, where every ingredient is chosen for its origin and nutritional quality. The menu, built around superfoods and simple recipes, champions local producers and cuts out unnecessary middlemen. From breakfast to evening cocktails, Silo proves that functional cooking, designed for longevity, can also be deeply enjoyable. Open Monday through Saturday from 7am to 10pm and Sunday from 7am to 1pm, the restaurant draws both hotel guests and neighborhood locals in search of a conscious pause.

Sastra, Colombia’s first longevity club

At the heart of Wake BioHotel, Sastra pushes the wellness experience toward the science of longevity. The club brings together a low-density pool designed for muscle decompression, a 24-hour gym, a detoxifying infrared sauna, a contrast-temperature jacuzzi, and a cold plunge pool built to stimulate the immune system. Three levels of diagnostics, from a basic body scan to a full analysis of blood biomarkers, allow guests to precisely assess their physiological state, while two membership tiers, Essential and Longevity Pro, unlock regular medical follow-ups and photobiomodulation sessions.

An address to rethink your relationship with time

Wake BioHotel promises more than a restful stay: it offers a new way of inhabiting time itself. Guests arrive to sleep better, and leave wanting to live better, for longer. A singular address, at the crossroads of hospitality and preventive medicine.

We love Wake BioHotel for

  • Colombia’s first longevity hotel
  • 109 rooms designed for deep sleep
  • The BioRoom and its cutting-edge technology
  • Silo’s real, traceable cooking
  • Sastra, longevity club, sauna and cold plunge
  • El Poblado, Medellín’s most vibrant district
Wake BioHotel
Wake BioHotel
Wake BioHotel
Wake BioHotel
Wake BioHotel
Wake BioHotel

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